Navigating health and well-being during the COVID-19 pandemic: Experiences of Latina immigrant mothers in rural Midwestern communities

Objective: In this study, we sought to gain insight into the challenges Latina immigrant mothers in rural Midwest communities encountered during the pandemic, strategies they employed to avoid infection of the virus, and impacts of the pandemic on family health and well-being. Background: In rural Midwestern communities, the pandemic disproportionately affected immigrants, many of whom are Latino and worked in meatpacking and food processing plants. Latina mothers are commonly viewed as caretakers of the family. This prescribed role placed mothers at the center of safeguarding their families' health during the pandemic. Method: In this descriptive study, we conducted individual interviews with 124 Latina immigrant mothers across six rural Midwestern communities who participated in one of two previous studies in the communities. Thematic analyses was used to identify themes that aligned with three areas of interest: challenges experienced, strategies employed to avoid virus infection, and impacts of the pandemic on family health and well-being. Results: Mothers enacted behaviors (e.g., sanitation practices, wore masks, stayed home) to lessen negative impacts of the pandemic on family health and well-being. Factors beyond their control (e.g., public policies, work policies and practices) placed families at greater risk for poor health and well-being. Eleven themes were identified that aligned with the three areas of interest. Conclusion: Findings build upon and extend prior research that reexposed unjust employment conditions, inadequate health-care systems, and an anti-immigrant context during the pandemic that perpetuated health disparities among Latino immigrants and other minoritized populations. Implications: Ethnographic and longitudinal studies that give voice to populations underrepresented in COVID-19 research and at high risk for poor health are warranted to inform policies and practices to protect health during public health crises. © 2023 The Authors. Family Relations published by Wiley Periodicals LLC on behalf of National Council on Family Relations.

Treatment Effects of Integrated TCM and Western Medicine Treatment Scheme on COVID-19: A Single-armed Clinical Trial

Backgroud: The outbreak of COVID-19 has brought unprecedented perils to human health and raised public health concerns in more than two hundred countries. Safe and effective treatment scheme is needed urgently. Objective(s): To evaluate the effects of integratedTCM and western medicine treatment scheme on COVID-19. Method(s): A single-armed clinical trial was carried out in Hangzhou Xixi Hospital, an affiliated hospital with Zhejiang Chinese Medical University. 102 confirmed cases were screened out from 725 suspected cases and 93 of them were treated with integrated TCM and western medicine treatment scheme. Result(s): 83 cases were cured, 5 cases deteriorated, and 5 cases withdrew from the study. No deaths were reported. The mean relief time of fever, cough, diarrhea, and fatigue were (4.78 +/- 4.61) days, (7.22 +/- 4.99) days, (5.28 +/- 3.39) days, and (5.28 +/- 3.39) days, respectively. It took (14.84 +/- 5.50) days for SARS-CoV-2 by nucleic acid amplification-based testing to turn negative. Multivariable cox regression analysis revealed that age, BMI, PISCT, BPC, AST, CK, BS, and UPRO were independent risk factors for COVID-19 treatment. Conclusion(s): Our study suggested that integrated TCM and western medicine treatment scheme was effective for COVID-19.Copyright © 2021

A bio-inspired LIDA cognitive-based Digital Twin architecture for unmanned maintenance of machine tools

Affected by COVID-19, the maintenance process of machine tools is significantly hindered, while unmanned maintenance becomes an emerging trend in such background. So far, three challenges, namely, the dependence on maintenance experts, the dynamic maintenance environments, and unsynchronized interactions between physical and information sides, exist as the main obstacles in its widespread applications. In order to fill this gap, a bio-inspired LIDA cognitive-based Digital Twin architecture is proposed, so as to achieve unmanned maintenance of machine tools through a self-constructed, self-evaluated, and self-optimized manner. A three phases process in the architecture, including the physical phase, virtual phase, and service phase, is further introduced to support the cognitive cycle for unmanned maintenance of machine tools. An illustrative example is depicted in the unmanned fault diagnosis on the rolling bearing of a drilling platform, which validates the feasibility and advantages of the proposed architecture. As an explorative study, it is wished that this work provides useful insights for unmanned maintenance of machine tools in a dynamic production environment. © 2022

Semen parameters and sex hormones as affected by SARS-CoV-2 infection: A systematic review.

BACKGROUND: Impaired semen quality and reproductive hormone levels were observed in patients during and after recovery from coronavirus disease 2019 (COVID-19), which raised concerns about negative effects on male fertility. Therefore, this study systematically reviews available data on semen parameters and sex hormones in patients with COVID-19. METHODS: Systematic search was performed on PubMed and Google Scholar until July 18th, 2022. We identified relevant articles that discussed the effects of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) on male fertility. RESULTS: A total number of 1,684 articles were identified by using a suitable keyword search strategy. After screening, 26 articles were considered eligible for inclusion in this study. These articles included a total of 1,960 controls and 2,106 patients. When all studies were considered, the results showed that the semen parameters and sex hormone levels of patients infected with SARS-CoV-2 exhibited some significant differences compared with controls. Fortunately, these differences gradually disappear as patients recover from COVID-19. CONCLUSION: While present data show the negative effects of SARS-CoV-2 infection on male fertility, this does not appear to be long-term. Semen quality and hormone levels will gradually increase to normal as patients recover.

Location-specific health impacts of climate change require location-specific responses

Left unmitigated, climate change poses a catastrophic risk to human health, demanding an urgent and concerted response from every country. The 2015 Lancet Commission on Health and Climate Change and The Lancet Countdown: Tracking Progress on Health and Climate Change have been initiated to map out the impacts of climate change and the necessary policy responses. To meet these challenges, Tsinghua University, partnering with the University College London and 17 Chinese and international institutions, has prepared the Chinese Lancet Countdown report, which has a national focus and builds on the work of the global Lancet Countdown: Tracking Progress on Health and Climate Change. Drawing on international methodologies and frameworks, this report aims to deepen the understanding of the links between public health and climate change at the national level and track them with 23 indicators. This work is part of the Lancet's Countdown broader efforts to develop regional expertise on this topic, and coincides with the launch of the Lancet Countdown Regional Centre in Asia, based at Tsinghua University. The data and results of this report are presented at the provincial level, where possible, to facilitate targeted response strategies for local decision-makers. Based on the data and findings of the 2020 Chinese Lancet Countdown report, five recommendations are proposed to key stakeholders in health and climate change in China: (1) Enhance inter-departmental cooperation. Climate change is a challenge that demands an integrated response from all sectors, urgently requiring substantial inter-departmental cooperation among health, environment, energy, economic, financial, and education authorities. (2) Strengthen health emergency preparedness. Knowledge and findings on current and future climate-related health threats still lack the required attention and should be fully integrated into the emergency preparedness and response system. (3) Support research and raise awareness. Additional financial support should be allocated to health and climate change research in China to enhance health system adaptation, mitigation measures, and their health benefits. At the same time, media and academia should be fully motivated to raise the public and politicians' awareness of this topic. (4) Increase climate change mitigation. Speeding up the phasing out of coal is necessary to be consistent with China's pledge to be carbon neutral by 2060 and to continue to reduce air pollution. Fossil fuel subsidies must also be phased out. (5) Ensure the recovery from COVID-19 to protect health now and in the future. China's efforts to recover from COVID-19 will shape public health for years to come. Climate change should be a priority in these interventions. © 2021, Science Press. All right reserved.

Research on the Development of Cross Border E-commerce based on Dual Chain Integration Mode

The outbreak of COVID-19 has a huge impact on the social economy. The development mode of the global economy and trade has also changed, which has accelerated the rapid development of cross-border e-commerce mode. Under the normal epidemic situation, how to optimize the development of cross-border e-commerce is the key to promote economic development. This paper analyzes the pain points of cross-border e-commerce. Based on the analysis of the whole industry chain of cross-border e-commerce, it deeply analyzes the relationship between blockchain and cross-border e-commerce. This paper puts forward the idea of blockchain enabling cross-border industrial chain to transform and develop cross-border e-commerce, and constructs a cross-border e-commerce system model based on blockchain, so as to promote the healthy and ecological development of cross-border e-commerce. © 2021 IEEE.

Potential efficacy of immunosuppressant in the treatment of COVID-19

The outbreak of COVID-19 has infected millions of people and caused hundreds of thousands of deaths worldwide. As there is no specific medicines or effective vaccines against 2019-nCoV at present, it is an alternative strategy to repurpose existing drugs for new diseases. Cyclosporin A inhibits the replication of coronaviruses by binding to cellular cyclophilins. Chloroquine/hydroxychloroquine can block virus-receptor binding through interfering with terminal glycosylation of the cellular receptor angiotensin-converting enzyme 2 (ACE2). Trastuzumab prevents the binding of IL-6 to both sIL-6R and mIL-6R and thereby inhibits the cytokine storm syndrome induced by COVID-19. This paper discussed the potential anti-2019-nCoV effects of some common immunosuppressant including cyclosporine, chloroquine/hydroxychloroquine, and tocilizumab.